Potato ketolide A
Taccalonolide A
CAS: 108885-68-3
Molecular Formula: C36H46O14
Potato ketolide A - Names and Identifiers
Potato ketolide A - Physico-chemical Properties
| Molecular Formula | C36H46O14 |
| Molar Mass | 702.74 |
| Density | 1.41±0.1 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 776.8±60.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.025 in CHCl3)+39.5 |
| Solubility | Insuluble (1.3E-3 g/L) (25 °C) |
| Appearance | Powder |
| pKa | 11.56±0.70(Predicted) |
| Storage Condition | 2-8℃ |
Potato ketolide A - Reference Information
| biological activity | Taccalonolide A is a microtubule stabilizer, a steroid isolated from Tacca chantrieri, with cytotoxicity and antimalarial activity. Taccalonolide A can cause G2-M phase retention, Bcl-2 phosphorylation and apoptosis. Taccalonolide A has significant inhibitory effect on cell lines overexpressing p glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7) in vitro, and the IC50 value of inhibiting SK-OV-3 cell growth is 622 nM. |
| target | microtubule |
Last Update：2024-04-09 02:00:01
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Product Name: Taccalonolide A Visit Supplier Webpage Request for quotationCAS: 108885-68-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Taccalonolide A Visit Supplier Webpage Request for quotationCAS: 108885-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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